The ongoing projects highlighted below are designed to improve cardiometabolic care either by demonstrating effectiveness or scaling to other health systems.
For more information about the projects, please reach out to the corresponding author in the publication or to the project contact.
Description
Aim
Build LDL-C testing and treatment awareness to action at point of care via Expert Consensus Decision Pathway-based care*
Methods
Prompts/reminders; education; performance dashboards
Audience Engaged
HCP; Health System
Resources Available
Learn more about this initiative here.
Project Contact:
Please reach out to
kbyrd@acc.org
for additional project information.
*ACC Driving Urgency to Treat LDL-C is a multi-sponsored effort.
Description
Aim
Improve LDL-C testing and treatment planning prior to ASCVD hospital discharge and minimizing loss to follow up prior to 6 months†
Methods
Prompts/reminders; Education; Navigators/care team model
Audience Engaged
Patient; HCP; Health system
Resources Available
Learn more about this initiative here.
Project Contact:
Please reach out to
lauren.w.cohen@duke.edu
for additional project information.
†CardioHealth Alliance (CHA) Test to Treat is a multi-sponsored effort through CHA.
Description
Aim
Determine the effectiveness of the holistic, patient-centered, coordinated team approach to cardiometabolic disease and improve the way care is delivered to this high-risk patient population, including patients with ASCVD [Anticipated completion date: Q2 2026]
Methods
Prompts/reminders; Performance dashboard
Audience Engaged
HCP; Health system
Resources Available
Learn more about this initiative here.
Project Contact:
Please reach out to
mmagwire@saint-lukes.org
for additional project information.
Description
Aim
Prospective registry to examine and track lipid-lowering therapy utilization and LDL-C levels in adults with ASCVD seen across 25 health systems over 5 years‡
Methods
Prospective registry; EHR data
Audience Engaged
HCP; Health System
Resources Available
Learn more about this initiative here.
Project Contact:
Please reach out to
ann.navar@utsouthwestern.edu
for additional project information.
‡cvMOBIUS2 is an Amgen sponsored trial in collaboration with DCRI and UTSW.
Description
Aim
Prospective study to evaluate a multifaceted site-level intervention (performance platform and education) to enhance clinicians’ adherence to guidelines to improve LDL-C levels for patients with very high risk ASCVD§
Methods
Prospective study; Education/Performance dashboard
Audience Engaged
HCP
Resources Available
McKoy, J Nikki et al. “LOGAN-CV: A Prospective Study of a Multifaceted Intervention Targeting United States Clinicians to Improve Guideline-Based Management of Lipid-Lowering Therapy.” Advances in Therapy vol. 41,1 (2024): 451-463. doi:10.1007/s12325-023-02716-6. https://pubmed.ncbi.nlm.nih.gov/37989909/
Learn more about this initiative here.
Project Contact:
Please reach out to
yosef_khan@premierinc.com
for additional project information.
§LOGAN-CV is an investigator-sponsored trial fully outsourced to Premier, Inc.
Description
Aim
Leverage computerized decision support tools to promote guideline-concordant, high-value, quality care for patients with very high risk ASCVD**
Methods
Prompts/reminders; education
Audience Engaged
HCP; Health System
Resources Available
PROMPT-Lipid:
Shah, Nimish N et al. “Rationale and design of a pragmatic trial aimed at improving treatment of hyperlipidemia in outpatients with very high risk atherosclerotic cardiovascular disease: A pragmatic trial of messaging to providers about treatment of hyperlipidemia (PROMPT-LIPID).” American Heart Journal vol. 253 (2022): 76-85. doi:10.1016/j.ahj.2022.07.002. https://pubmed.ncbi.nlm.nih.gov/35841944
Learn more about this initiative here.
Project Contact:
Please reach out to
ralph.rielloiii@yale.edu
for additional project information.
**PROMPT-LIPID Multicenter Registry Study takes the learnings from an Amgen investigator-initiated study and provides Amgen financial support for scaling.
We welcome ideas for improving patient care that are rooted in implementation science.
Reach us at LATTICEConsortium@amgen.com to connect with peers and institutions who have track records in implementation and scaling.