Ongoing Initiatives

The ongoing projects highlighted below are designed to improve cardiometabolic care either by demonstrating effectiveness or scaling to other health systems.


For more information about the projects, please reach out to the corresponding author in the publication or to the project contact.

  • ACC Driving Urgency to Treat LDL-C

    Description

    Aim

    Build LDL-C testing and treatment awareness to action at point of care via Expert Consensus Decision Pathway-based care*

    Methods

    Prompts/reminders; education; performance dashboards

    Audience Engaged

    HCP; Health System

    Resources Available

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    kbyrd@acc.org
    for additional project information.


    *ACC Driving Urgency to Treat LDL-C is a multi-sponsored effort.

  • CHA Test to Treat

    Description

    Aim

    Improve LDL-C testing and treatment planning prior to ASCVD hospital discharge and minimizing loss to follow up prior to 6 months

    Methods

    Prompts/reminders; Education; Navigators/care team model

    Audience Engaged

    Patient; HCP; Health system

    Resources Available

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    lauren.w.cohen@duke.edu
    for additional project information.


    CardioHealth Alliance (CHA) Test to Treat is a multi-sponsored effort through CHA.

  • CMCA project

    Description

    Aim

    Determine the effectiveness of 
the holistic, patient-centered, coordinated team approach to cardiometabolic disease and improve the way care is delivered to this high-risk patient population, including patients with ASCVD [Anticipated completion date: Q2 2026]

    Methods

    Prompts/reminders; Performance dashboard

    Audience Engaged

    HCP; Health system

    Resources Available

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    mmagwire@saint-lukes.org
    for additional project information.

  • cvMOBIUS2

    Description

    Aim

    Prospective registry to examine and track lipid-lowering therapy utilization and LDL-C levels in adults with ASCVD seen across 25 health systems over 5 years

    Methods

    Prospective registry; EHR data

    Audience Engaged

    HCP; Health System

    Resources Available

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    ann.navar@utsouthwestern.edu
    for additional project information.


    cvMOBIUS2 is an Amgen sponsored trial in collaboration with DCRI and UTSW.

  • LOGAN-CV

    Description

    Aim

    Prospective study to evaluate a multifaceted site-level intervention (performance platform and education) to enhance clinicians’ adherence to guidelines to improve LDL-C levels for patients with very high risk ASCVD§

    Methods

    Prospective study; Education/Performance dashboard

    Audience Engaged

    HCP

    Resources Available

    McKoy, J Nikki et al. “LOGAN-CV: A Prospective Study of a Multifaceted Intervention Targeting United States Clinicians to Improve Guideline-Based Management of Lipid-Lowering Therapy.” Advances in Therapy vol. 41,1 (2024): 451-463. doi:10.1007/s12325-023-02716-6. https://pubmed.ncbi.nlm.nih.gov/37989909/

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    yosef_khan@premierinc.com
    for additional project information.


    §LOGAN-CV is an investigator-sponsored trial fully outsourced to Premier, Inc.

  • PROMPT-Lipid Multicenter Registry Study

    Description

    Aim

    Leverage computerized decision support tools to promote guideline-concordant, high-value, quality care for patients with very high risk ASCVD**

    Methods

    Prompts/reminders; education

    Audience Engaged

    HCP; Health System

    Resources Available

    PROMPT-Lipid:

    Shah, Nimish N et al. “Rationale and design of a pragmatic trial aimed at improving treatment of hyperlipidemia in outpatients with very high risk atherosclerotic cardiovascular disease: A pragmatic trial of messaging to providers about treatment of hyperlipidemia (PROMPT-LIPID).” American Heart Journal vol. 253 (2022): 76-85. doi:10.1016/j.ahj.2022.07.002. https://pubmed.ncbi.nlm.nih.gov/35841944

    Learn more about this initiative here

    Project Contact:

    Please reach out to
    ralph.rielloiii@yale.edu
    for additional project information.

    **PROMPT-LIPID Multicenter Registry Study takes the learnings from an Amgen investigator-initiated study and provides Amgen financial support for scaling.

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